EC 7.5.2.1: ABC-type maltose transporter
Reaction catalysed:
ATP + H(2)O + maltose-[maltose-binding protein](Side 1) = ADP + phosphate + maltose(Side 2) + [maltose-binding protein](Side 1)
Systematic name:
ATP phosphohydrolase (ABC-type, maltose-importing)
Alternative Name(s):
- Maltose ABC transporter
- Maltose-transporting ATPase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
PF00528
Domain description:
Binding-protein-dependent transport system inner membrane component
Occurring in:
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 1 copy of Pfam domain <span class='highlight'>PF00528 (Binding-protein-dependent transport system inner membrane component)</span> in <span class='highlight'>Maltose/maltodextrin transport system permease protein MalF</span>. Showing 1 copy in chain <span class='highlight'>B [auth F]</span>. The deposited structure of PDB entry 3puw contains 1 copy of Pfam domain PF00528 (Binding-protein-dependent transport system inner membrane component) in Maltose/maltodextrin transport system permease protein MalF. Showing 1 copy in chain B [auth F].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_2_F_Pfam_PF00528_image-200x200.png)
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 1 copy of Pfam domain <span class='highlight'>PF00528 (Binding-protein-dependent transport system inner membrane component)</span> in <span class='highlight'>Maltose/maltodextrin transport system permease protein MalG</span>. Showing 1 copy in chain <span class='highlight'>C [auth G]</span>. The deposited structure of PDB entry 3puw contains 1 copy of Pfam domain PF00528 (Binding-protein-dependent transport system inner membrane component) in Maltose/maltodextrin transport system permease protein MalG. Showing 1 copy in chain C [auth G].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_3_G_Pfam_PF00528_image-200x200.png)
InterPro annotations
IPR006060
Domain description:
Maltose/Cyclodextrin ABC transporter, substrate-binding protein
Occurring in:
Occurring in:
IPR047103
Domain description:
Maltose transport system permease protein MalF, P2 domain superfamily
Occurring in:
Occurring in:
IPR029345
Domain description:
Maltose transport system permease protein MalF, P2 domain
Occurring in:
Occurring in:
Structure domains
CATH domains
3.40.190.10
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
D-Maltodextrin-Binding Protein; domain 2
Homology:
Periplasmic binding protein-like II
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 2 copies of CATH domain <span class='highlight'>3.40.190.10 (D-Maltodextrin-Binding Protein; domain 2)</span> in <span class='highlight'>Maltose/maltodextrin-binding periplasmic protein</span>. Showing 2 copies in chain <span class='highlight'>A [auth E]</span>. The deposited structure of PDB entry 3puw contains 2 copies of CATH domain 3.40.190.10 (D-Maltodextrin-Binding Protein; domain 2) in Maltose/maltodextrin-binding periplasmic protein. Showing 2 copies in chain A [auth E].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_1_E_CATH_3.40.190.10_image-200x200.png)
2.40.50.100
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 2 copies of CATH domain <span class='highlight'>2.40.50.100 (OB fold (Dihydrolipoamide Acetyltransferase, E2P))</span> in <span class='highlight'>Maltose/maltodextrin import ATP-binding protein MalK</span>. Showing 1 copy in chain <span class='highlight'>D [auth A]</span>. The deposited structure of PDB entry 3puw contains 2 copies of CATH domain 2.40.50.100 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Maltose/maltodextrin import ATP-binding protein MalK. Showing 1 copy in chain D [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_4_A_CATH_2.40.50.100_image-200x200.png)
1.10.3720.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
MetI-like fold
Homology:
MetI-like
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 1 copy of CATH domain <span class='highlight'>1.10.3720.10 (MetI-like fold)</span> in <span class='highlight'>Maltose/maltodextrin transport system permease protein MalF</span>. Showing 1 copy in chain <span class='highlight'>B [auth F]</span>. The deposited structure of PDB entry 3puw contains 1 copy of CATH domain 1.10.3720.10 (MetI-like fold) in Maltose/maltodextrin transport system permease protein MalF. Showing 1 copy in chain B [auth F].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_2_F_CATH_1.10.3720.10_image-200x200.png)
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 1 copy of CATH domain <span class='highlight'>1.10.3720.10 (MetI-like fold)</span> in <span class='highlight'>Maltose/maltodextrin transport system permease protein MalG</span>. Showing 1 copy in chain <span class='highlight'>C [auth G]</span>. The deposited structure of PDB entry 3puw contains 1 copy of CATH domain 1.10.3720.10 (MetI-like fold) in Maltose/maltodextrin transport system permease protein MalG. Showing 1 copy in chain C [auth G].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_3_G_CATH_1.10.3720.10_image-200x200.png)
3.10.650.10
Class:
Alpha Beta
Architecture:
Roll
Topology:
MalF N-terminal region-like
Homology:
MalF N-terminal region-like
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 1 copy of CATH domain <span class='highlight'>3.10.650.10 (MalF N-terminal region-like)</span> in <span class='highlight'>Maltose/maltodextrin transport system permease protein MalF</span>. Showing 1 copy in chain <span class='highlight'>B [auth F]</span>. The deposited structure of PDB entry 3puw contains 1 copy of CATH domain 3.10.650.10 (MalF N-terminal region-like) in Maltose/maltodextrin transport system permease protein MalF. Showing 1 copy in chain B [auth F].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_2_F_CATH_3.10.650.10_image-200x200.png)
2.40.50.140
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology:
Nucleic acid-binding proteins
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 2 copies of CATH domain <span class='highlight'>2.40.50.140 (OB fold (Dihydrolipoamide Acetyltransferase, E2P))</span> in <span class='highlight'>Maltose/maltodextrin import ATP-binding protein MalK</span>. Showing 1 copy in chain <span class='highlight'>D [auth A]</span>. The deposited structure of PDB entry 3puw contains 2 copies of CATH domain 2.40.50.140 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Maltose/maltodextrin import ATP-binding protein MalK. Showing 1 copy in chain D [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_4_A_CATH_2.40.50.140_image-200x200.png)
3.40.50.300
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Rossmann fold
Homology:
P-loop containing nucleotide triphosphate hydrolases
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 2 copies of CATH domain <span class='highlight'>3.40.50.300 (Rossmann fold)</span> in <span class='highlight'>Maltose/maltodextrin import ATP-binding protein MalK</span>. Showing 1 copy in chain <span class='highlight'>D [auth A]</span>. The deposited structure of PDB entry 3puw contains 2 copies of CATH domain 3.40.50.300 (Rossmann fold) in Maltose/maltodextrin import ATP-binding protein MalK. Showing 1 copy in chain D [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_4_A_CATH_3.40.50.300_image-200x200.png)
2.40.430.10
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
Periplasmic binding protein-like II
Homology:
D-maltodextrin-binding protein, MBP
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3puw</span> contains 1 copy of CATH domain <span class='highlight'>2.40.430.10 (Periplasmic binding protein-like II)</span> in <span class='highlight'>Maltose/maltodextrin transport system permease protein MalF</span>. Showing 1 copy in chain <span class='highlight'>B [auth F]</span>. The deposited structure of PDB entry 3puw contains 1 copy of CATH domain 2.40.430.10 (Periplasmic binding protein-like II) in Maltose/maltodextrin transport system permease protein MalF. Showing 1 copy in chain B [auth F].](https://www.ebi.ac.uk/pdbe/static/entry/3puw_2_F_CATH_2.40.430.10_image-200x200.png)