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Crystal Structure of CFIm68 RRM/CFIm25 complex

Source organism: Homo sapiens
Biochemical function: RNA binding
Biological process: positive regulation of pro-B cell differentiation
Cellular component: paraspeckles

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00076
Domain description: RNA recognition motif
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 6
The deposited structure of PDB entry 3q2s contains 2 copies of Pfam domain PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) in Cleavage and polyadenylation specificity factor subunit 6. Showing 1 copy in chain C.

PF13869
Domain description: Nucleotide hydrolase
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 5
The deposited structure of PDB entry 3q2s contains 2 copies of Pfam domain PF13869 (Nucleotide hydrolase) in Cleavage and polyadenylation specificity factor subunit 5. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000504
Domain description: RNA recognition motif domain
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 6
IPR016706
Domain description: Cleavage/polyadenylation specificity factor subunit 5
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 5
IPR035979
Domain description: RNA-binding domain superfamily
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 6
IPR034769
Domain description: Cleavage and polyadenylation specificity factor subunit 6, RNA recognition motif
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 6
IPR012677
Domain description: Nucleotide-binding alpha-beta plait domain superfamily
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 6
IPR034772
Domain description: CPSF6/7 family
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 6
IPR015797
Domain description: NUDIX hydrolase-like domain superfamily
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 5
IPR000086
Domain description: NUDIX hydrolase domain
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 5

Structure domains

CATH CATH domains
3.30.70.330
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Alpha-Beta Plaits
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 6
The deposited structure of PDB entry 3q2s contains 2 copies of CATH domain 3.30.70.330 (Alpha-Beta Plaits) in Cleavage and polyadenylation specificity factor subunit 6. Showing 1 copy in chain C.
3.90.79.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Nucleoside Triphosphate Pyrophosphohydrolase
Homology: Nucleoside Triphosphate Pyrophosphohydrolase
Occurring in:
  1. Cleavage and polyadenylation specificity factor subunit 5
The deposited structure of PDB entry 3q2s contains 2 copies of CATH domain 3.90.79.10 (Nucleoside Triphosphate Pyrophosphohydrolase) in Cleavage and polyadenylation specificity factor subunit 5. Showing 1 copy in chain A.

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