› 3qje

X-ray diffraction
1.8Å resolution

Human Hemoglobin A Mutant Beta H63L Deoxy-Form

Released:
DOI: 10.2210/pdb3qje/pdb
PDB entry 3qje coloured by chain, front view.
PDB entry 3qje coloured by chain, side view.
PDB entry 3qje coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Determination of Pathways for Oxygen Binding to Human HbA
Birukou I, Soman J, Olson JS
To be published

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159519 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: A, C
Molecule details ›
Chains: A, C
Length: 141 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P69905 (Residues: 2-142; Coverage: 99%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chains: B, D
Molecule details ›
Chains: B, D
Length: 146 amino acids
Theoretical weight: 15.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 4 x HEM
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21
Unit cell:
a: 62.42Å b: 81.38Å c: 53.52Å
α: 90° β: 99.56° γ: 90°
R-values:
R R work R free
0.201 0.199 0.243
Expression system: Escherichia coli

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