› 3qor

X-ray diffraction
1.75Å resolution

Crystal structure of human nuclear migration protein NudC

Released:
DOI: 10.2210/pdb3qor/pdb
PDB entry 3qor coloured by chain, front view.
PDB entry 3qor coloured by chain, side view.
PDB entry 3qor coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural features and chaperone activity of the NudC protein family.
Zheng M, Cierpicki T, Burdette AJ, Utepbergenov D, Janczyk PŁ, Derewenda U, Stukenberg PT, Caldwell KA, Derewenda ZS
J Mol Biol 409 722-41 (2011)
PMID: 21530541

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195106 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Nuclear migration protein nudC Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y266 (Residues: 158-274; Coverage: 35%)
Gene name: NUDC
Sequence domains: CS domain
Structure domains: Immunoglobulin-like
Nuclear migration protein nudC Chain: B
Molecule details ›
Chain: B
Length: 121 amino acids
Theoretical weight: 13.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y266 (Residues: 158-274; Coverage: 35%)
Gene name: NUDC
Sequence domains: CS domain
Structure domains: Immunoglobulin-like
Nuclear migration protein nudC Chain: C
Molecule details ›
Chain: C
Length: 121 amino acids
Theoretical weight: 13.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y266 (Residues: 158-274; Coverage: 35%)
Gene name: NUDC
Sequence domains: CS domain
Structure domains: Immunoglobulin-like
Nuclear migration protein nudC Chains: D, E
Molecule details ›
Chains: D, E
Length: 121 amino acids
Theoretical weight: 13.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y266 (Residues: 158-274; Coverage: 35%)
Gene name: NUDC
Sequence domains: CS domain
Structure domains: Immunoglobulin-like

Ligands and Environments

1 bound ligand:
Ligand ACT 1 x ACT
3 modified residues:
Ligand CSX 1 x CSX
Ligand CSD 1 x CSD
Ligand OCS 2 x OCS

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 66.734Å b: 51.82Å c: 92.854Å
α: 90° β: 90.58° γ: 90°
R-values:
R R work R free
0.174 0.173 0.202
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The 'active life' of Hsp90 complexes.
Prodromou C. (2012)
4 more

2 mentions without citation

Structural features and chaperone activity of the NudC protein family.
Zheng et al. (2011)
1 more