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Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8

Source organisms:
Biochemical function: toxin activity
Biological process: modulation of process of another organism
Cellular component: extracellular region

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF02876
Domain description: Staphylococcal/Streptococcal toxin, beta-grasp domain
Occurring in:
  1. Enterotoxin type B
The deposited structure of PDB entry 3r8b contains 8 copies of Pfam domain PF02876 (Staphylococcal/Streptococcal toxin, beta-grasp domain) in Enterotoxin type B. Showing 1 copy in chain I.

PF01123
Domain description: Staphylococcal/Streptococcal toxin, OB-fold domain
Occurring in:
  1. Enterotoxin type B
The deposited structure of PDB entry 3r8b contains 8 copies of Pfam domain PF01123 (Staphylococcal/Streptococcal toxin, OB-fold domain) in Enterotoxin type B. Showing 1 copy in chain I.

InterPro InterPro annotations
IPR013307
Domain description: Superantigen, staphylococcal/streptococcal toxin, bacterial
Occurring in:
  1. Enterotoxin type B
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. G5-8
IPR006126
Domain description: Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site
Occurring in:
  1. Enterotoxin type B
IPR006177
Domain description: Staphylococcal/streptococcal toxin, bacterial
Occurring in:
  1. Enterotoxin type B
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. G5-8
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. G5-8
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. G5-8
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. G5-8
IPR006123
Domain description: Staphylococcal/Streptococcal toxin, beta-grasp domain
Occurring in:
  1. Enterotoxin type B
IPR016091
Domain description: Superantigen toxin, C-terminal
Occurring in:
  1. Enterotoxin type B
IPR006173
Domain description: Staphylococcal/Streptococcal toxin, OB-fold
Occurring in:
  1. Enterotoxin type B
IPR008992
Domain description: Enterotoxin
Occurring in:
  1. Enterotoxin type B

Structure domains

CATH CATH domains
3.10.20.120
Class: Alpha Beta
Architecture: Roll
Topology: Ubiquitin-like (UB roll)
Homology: Ubiquitin-like (UB roll)
Occurring in:
  1. Enterotoxin type B
The deposited structure of PDB entry 3r8b contains 8 copies of CATH domain 3.10.20.120 (Ubiquitin-like (UB roll)) in Enterotoxin type B. Showing 1 copy in chain I.
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. G5-8
The deposited structure of PDB entry 3r8b contains 8 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in G5-8. Showing 1 copy in chain B.
2.40.50.110
Class: Mainly Beta
Architecture: Beta Barrel
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
  1. Enterotoxin type B
The deposited structure of PDB entry 3r8b contains 8 copies of CATH domain 2.40.50.110 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Enterotoxin type B. Showing 1 copy in chain I.

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