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3s3n Overview
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>3s3n</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_deposited_chain_front_image-800x800.png "PDB entry 3s3n coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>3s3n</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_deposited_chain_side_image-800x800.png "PDB entry 3s3n coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>3s3n</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_deposited_chain_top_image-800x800.png "PDB entry 3s3n coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>3s3n</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 3s3n coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>3s3n</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 3s3n coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>3s3n</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 3s3n coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Hetero octameric assembly 1 of PDB entry <span class='highlight'>3s3n</span> contains 2 copies of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_entity_9_front_image-800x800.png "(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide in PDB entry 3s3n, assembly 1, front view.")
![<div class='caption-body'>Hetero octameric assembly 1 of PDB entry <span class='highlight'>3s3n</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>6 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>8 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Hetero octameric assembly 1 of PDB entry 3s3n coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Hetero octameric assembly 1 of PDB entry <span class='highlight'>3s3n</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>6 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>8 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Hetero octameric assembly 1 of PDB entry 3s3n coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Hetero octameric assembly 1 of PDB entry <span class='highlight'>3s3n</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>Integrase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>6 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>8 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>AMMONIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/3s3n_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Hetero octameric assembly 1 of PDB entry 3s3n coloured by chemically distinct molecules, top view.")