Function and Biology Details
Reaction catalysed:
Fully activates human clotting factor V by a single cleavage at the 1545-Trp-Tyr-Leu-Arg-|-Ser-Asn-Asn-Gly-1552 bond. Cattle, but not rabbit, factor V is cleaved, and no other proteins of the clotting system are attacked. Esterase activity is observed on Bz-Arg-OEt and Tos-Arg-OMe, and amidase activity on Phe-pipecolyl-Arg-NHPhNO(2).
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Factor V activator RVV-V gamma (preferred)
PDBe Complex ID:
PDB-CPX-148484 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Factor V activator RVV-V gamma
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 25.96 KDa
Source organism: Daboia siamensis
UniProt:
Structure domains: Trypsin-like serine proteases
Length: 234 amino acids
Theoretical weight: 25.96 KDa
Source organism: Daboia siamensis
UniProt:
- Canonical:
P18965 (Residues: 25-260; Coverage: 97%)
Structure domains: Trypsin-like serine proteases
