Function and Biology

Sac3:Thp1:Sem1 complex

Source organism: Saccharomyces cerevisiae

Sequence families

Pfam Protein families (Pfam)
PF05160
Domain description: DSS1/SEM1 family
Occurring in:
  1. 26S proteasome complex subunit SEM1
The deposited structure of PDB entry 3t5v contains 2 copies of Pfam domain PF05160 (DSS1/SEM1 family) in 26S proteasome complex subunit SEM1. Showing 1 copy in chain C.

PF01399
Domain description: PCI domain
Occurring in:
  1. Nuclear mRNA export protein THP1
The deposited structure of PDB entry 3t5v contains 2 copies of Pfam domain PF01399 (PCI domain) in Nuclear mRNA export protein THP1. Showing 1 copy in chain B.

PF03399
Domain description: SAC3/GANP family
Occurring in:
  1. Nuclear mRNA export protein SAC3
The deposited structure of PDB entry 3t5v contains 2 copies of Pfam domain PF03399 (SAC3/GANP family) in Nuclear mRNA export protein SAC3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR007834
Domain description: DSS1/SEM1
Occurring in:
  1. 26S proteasome complex subunit SEM1
IPR000717
Domain description: Proteasome component (PCI) domain
Occurring in:
  1. Nuclear mRNA export protein SAC3
  2. Nuclear mRNA export protein THP1
IPR045114
Domain description: Csn12 family
Occurring in:
  1. Nuclear mRNA export protein THP1
IPR045107
Domain description: SAC3/GANP/THP3
Occurring in:
  1. Nuclear mRNA export protein SAC3
IPR005062
Domain description: SAC3/GANP/THP3, conserved domain
Occurring in:
  1. Nuclear mRNA export protein SAC3

Structure domains

CATH CATH domains
1.25.40.990
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Occurring in:
  1. Nuclear mRNA export protein SAC3
The deposited structure of PDB entry 3t5v contains 2 copies of CATH domain 1.25.40.990 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Nuclear mRNA export protein SAC3. Showing 1 copy in chain A.
6.10.250.1210
Class: Special
Architecture: Helix non-globular
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Occurring in:
  1. 26S proteasome complex subunit SEM1
The deposited structure of PDB entry 3t5v contains 1 copy of CATH domain 6.10.250.1210 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in 26S proteasome complex subunit SEM1. Showing 1 copy in chain F.