EC 3.1.1.4: Phospholipase A(2)
Reaction catalysed:
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Systematic name:
Phosphatidylcholine 2-acylhydrolase
Alternative Name(s):
- Lecithinase A
- Phosphatidase
- Phosphatidolipase
- Phospholipase A
- Phospholipase A2
GO terms
Biochemical function:
Biological process:
- regulation of neutrophil activation
- positive regulation of ERK1 and ERK2 cascade
- defense response to Gram-positive bacterium
- positive regulation of inflammatory response
- arachidonate secretion
- phosphatidic acid metabolic process
- phosphatidylcholine metabolic process
- phosphatidylethanolamine metabolic process
- defense response to bacterium
- negative regulation of T cell proliferation
- intestinal stem cell homeostasis
- low-density lipoprotein particle remodeling
- killing of cells of another organism
- lipid catabolic process
- positive regulation of macrophage derived foam cell differentiation
- inflammatory response
- phospholipid metabolic process
- lipid metabolic process
Protein family (Pfam)
InterPro annotations
CATH domain