› 3v55

X-ray diffraction
1.81Å resolution

Human MALT1 (334-719) in its ligand free form

Released:
DOI: 10.2210/pdb3v55/pdb
PDB entry 3v55 coloured by chain, front view.
PDB entry 3v55 coloured by chain, side view.
PDB entry 3v55 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural determinants of MALT1 protease activity.
Wiesmann C, Leder L, Blank J, Bernardi A, Melkko S, Decock A, D'Arcy A, Villard F, Erbel P, Hughes N, Freuler F, Nikolay R, Alves J, Bornancin F, Renatus M
J Mol Biol 419 4-21 (2012)
PMID: 22366302

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-577379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Chain: A
Molecule details ›
Chain: A
Length: 389 amino acids
Theoretical weight: 43.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UDY8 (Residues: 334-719; Coverage: 47%)
Gene names: MALT1, MLT
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 96.65Å b: 67.25Å c: 58.04Å
α: 90° β: 97.31° γ: 90°
R-values:
R R work R free
0.198 0.196 0.238
Expression system: Escherichia coli

Quick links

Citations

10 review citations

A primer on caspase mechanisms.
Ramirez et al. (2018)
9 more

7 mentions without citation

The CBM signalosome: potential therapeutic target for aggressive lymphoma?
Yang et al. (2014)
6 more