› 3w58

X-ray diffraction
1.58Å resolution

Crystal structure of Galectin-1 in the lactose-unbound state(P21)

Released:
DOI: 10.2210/pdb3w58/pdb
PDB entry 3w58 coloured by chain, front view.
PDB entry 3w58 coloured by chain, side view.
PDB entry 3w58 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Saburi H, Tanaka T, Kunishima N

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140624 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 134 amino acids
Theoretical weight: 14.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09382 (Residues: 2-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:
Ligand BME 7 x BME
Ligand GOL 4 x GOL
Ligand SO4 5 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21
Unit cell:
a: 67.461Å b: 58.038Å c: 93.762Å
α: 90° β: 92.72° γ: 90°
R-values:
R R work R free
0.217 0.217 0.233
Expression system: Escherichia coli

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