EC 1.1.1.276: Serine 3-dehydrogenase (NADP(+))
Reaction catalysed:
(1a) L-serine + NADP(+) = 2-aminomalonate semialdehyde + NADPH
Systematic name:
L-serine:NADP(+) 3-oxidoreductase
Alternative Name(s):
- Serine 3-dehydrogenase
GO terms
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence families
Protein families (Pfam)
InterPro annotations
IPR029154
Domain description:
3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain
Occurring in:
Occurring in:
IPR008927
Domain description:
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Occurring in:
Occurring in:
IPR002204
Domain description:
3-hydroxyisobutyrate dehydrogenase-related, conserved site
Occurring in:
Occurring in:
Structure domains
CATH domains
1.10.1040.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Homology:
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>3w6u</span> contains 1 copy of CATH domain <span class='highlight'>1.10.1040.10 (N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2)</span> in <span class='highlight'>6-phosphogluconate dehydrogenase, NAD-binding protein</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 3w6u contains 1 copy of CATH domain 1.10.1040.10 (N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2) in 6-phosphogluconate dehydrogenase, NAD-binding protein. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/3w6u_1_A_CATH_1.10.1040.10_image-200x200.png)