› 3whk

X-ray diffraction
2.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152572 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
26S proteasome regulatory subunit 6A; Proteasome-activating nucleotidase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 270 amino acids
Theoretical weight: 30.02 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: Q8U4H3 (Residues: 125-309; Coverage: 47%)
  • Canonical: P33297 (Residues: 356-434; Coverage: 18%)
Gene names: O3258, PF0115, RPT5, YOR117W, YOR3258W, YTA1, pan
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ATP 8 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P1
Unit cell:
a: 71.04Å b: 85.76Å c: 105.26Å
α: 90.04° β: 90.03° γ: 89.89°
R-values:
R R work R free
0.243 0.242 0.275
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Regulation of proteasome assembly and activity in health and disease.
Rousseau et al. (2018)
5 more

3 mentions without citation

Mycobacterium tuberculosis proteasomal ATPase Mpa has a β-grasp domain that hinders docking with the proteasome core protease.
Wu et al. (2017)
2 more