› 3wkv

X-ray diffraction
3.45Å resolution

Voltage-gated proton channel: VSOP/Hv1 chimeric channel

Released:
DOI: 10.2210/pdb3wkv/pdb
PDB entry 3wkv coloured by chain, front view.
PDB entry 3wkv coloured by chain, side view.
PDB entry 3wkv coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
X-ray crystal structure of voltage-gated proton channel.
Takeshita K, Sakata S, Yamashita E, Fujiwara Y, Kawanabe A, Kurokawa T, Okochi Y, Matsuda M, Narita H, Okamura Y, Nakagawa A
Nat Struct Mol Biol 21 352-7 (2014)
PMID: 24584463

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-559178 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-gated hydrogen channel 1 Chain: A
Molecule details ›
Chain: A
Length: 196 amino acids
Theoretical weight: 22.88 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q3U2S8 (Residues: 73-160, 161-259; Coverage: 64%)
Gene names: Bts, Hvcn1, Vsop
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: P63
Unit cell:
a: 86.54Å b: 86.54Å c: 89.553Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.342 0.341 0.357
Expression system: Spodoptera frugiperda

Quick links

Citations

29 review citations

BK channels: multiple sensors, one activation gate.
Yang et al. (2015)
28 more

32 mentions without citation

Global versus local mechanisms of temperature sensing in ion channels.
Arrigoni et al. (2018)
31 more