Function and Biology

Crystal structure of Rv3378c with PO4

Source organism: Mycobacterium tuberculosis
Biochemical function: (13S)-vitexifolin A synthase activity
Biological process: response to host immune response
Cellular component: not assigned

EC 2.5.1.153: Adenosine tuberculosinyltransferase

Reaction catalysed:
Tuberculosinyl diphosphate + adenosine = 1-tuberculosinyladenosine + diphosphate
Systematic name:
Tuberculosinyl diphosphate:adenosine tuberculosinyltransferase
Alternative Name(s):
  • Rv3378c

Sequence family

InterPro InterPro annotation
IPR036424
Domain description: Decaprenyl diphosphate synthase-like superfamily
Occurring in:
  1. Tuberculosinyl adenosine transferase

Structure domain

CATH CATH domain
3.40.1180.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Undecaprenyl pyrophosphate synthetase
Homology: Decaprenyl diphosphate synthase-like
Occurring in:
  1. Tuberculosinyl adenosine transferase
The deposited structure of PDB entry 3wqk contains 1 copy of CATH domain 3.40.1180.10 (Undecaprenyl pyrophosphate synthetase) in Tuberculosinyl adenosine transferase. Showing 1 copy in chain A.