› 3wuq

X-ray diffraction
3.5Å resolution

Structure of the entire stalk region of the dynein motor domain

Released:
DOI: 10.2210/pdb3wuq/pdb
PDB entry 3wuq coloured by chain, front view.
PDB entry 3wuq coloured by chain, side view.
PDB entry 3wuq coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of the entire stalk region of the Dynein motor domain.
Nishikawa Y, Oyama T, Kamiya N, Kon T, Toyoshima YY, Nakamura H, Kurisu G
J Mol Biol 426 3232-3245 (2014)
PMID: 25058684

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191597 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoplasmic dynein 1 heavy chain 1 Chain: A
Molecule details ›
Chain: A
Length: 283 amino acids
Theoretical weight: 32.43 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JHU4 (Residues: 3207-3483; Coverage: 6%)
Gene names: Dhc1, Dnch1, Dnchc1, Dyhc, Dync1h1
Sequence domains: Microtubule-binding stalk of dynein motor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P3121
Unit cell:
a: 102.939Å b: 102.939Å c: 69.069Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.28 0.279 0.305
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Coiled-coils: The long and short of it.
Truebestein et al. (2016)
3 more

4 mentions without citation

Structural atlas of dynein motors at atomic resolution.
Toda et al. (2018)
3 more