› 4agg

X-ray diffraction
2.98Å resolution

Structure of a tetrameric galectin from Cinachyrella sp. (Ball sponge)

Released:
DOI: 10.2210/pdb4agg/pdb
PDB entry 4agg coloured by chain, front view.
PDB entry 4agg coloured by chain, side view.
PDB entry 4agg coloured by chain, top view.
Source organism: Cinachyrella
Primary publication:
Structure of a tetrameric galectin from Cinachyrella sp. (ball sponge).
Freymann DM, Nakamura Y, Focia PJ, Sakai R, Swanson GT
Acta Crystallogr D Biol Crystallogr 68 1163-74 (2012)
PMID: 22948917

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-515960 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin Chains: A, B
Molecule details ›
Chains: A, B
Length: 146 amino acids
Theoretical weight: 16.07 KDa
Source organism: Cinachyrella
UniProt:
  • Canonical: I0IV54 (Residues: 1-146; Coverage: 100%)
Gene name: CchGc
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: C2221
Unit cell:
a: 61.005Å b: 126.635Å c: 80.436Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.186 0.275

Quick links

Citations

3 review citations

Recent progress in neuroactive marine natural products.
Sakai et al. (2014)
2 more

2 mentions without citation

Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds.
Grizot et al. (2010)
1 more