› 4eed

X-ray diffraction
3.92Å resolution

CorA coiled-coil mutant under Mg2+ presence

Released:
DOI: 10.2210/pdb4eed/pdb
PDB entry 4eed coloured by chain, front view.
PDB entry 4eed coloured by chain, side view.
PDB entry 4eed coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation.
Pfoh R, Li A, Chakrabarti N, Payandeh J, Pomès R, Pai EF
Proc Natl Acad Sci U S A 109 18809-14 (2012)
PMID: 23112165

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cobalt/magnesium transport protein CorA Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 330 amino acids
Theoretical weight: 38.93 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9WZ31 (Residues: 26-351; Coverage: 93%)
Gene names: TM_0561, corA
Sequence domains: CorA-like Mg2+ transporter protein
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand MG 14 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P212121
Unit cell:
a: 121.7Å b: 132.5Å c: 179.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.3 0.297 0.351
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Mitochondrial channels: ion fluxes and more.
Szabo et al. (2014)
5 more

2 mentions without citation

Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation.
Pfoh et al. (2012)
1 more