› 4fhl

X-ray diffraction
2.6Å resolution

Nucleoporin Nup37 from Schizosaccharomyces pombe

Released:
DOI: 10.2210/pdb4fhl/pdb
PDB entry 4fhl coloured by chain, front view.
PDB entry 4fhl coloured by chain, side view.
PDB entry 4fhl coloured by chain, top view.
Source organism: Schizosaccharomyces pombe 972h-
Primary publication:
Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex.
Bilokapic S, Schwartz TU
Proc Natl Acad Sci U S A 109 15241-6 (2012)
PMID: 22955883

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-519808 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uncharacterized WD repeat-containing protein C4F10.18 Chain: A
Molecule details ›
Chain: A
Length: 394 amino acids
Theoretical weight: 43.05 KDa
Source organism: Schizosaccharomyces pombe 972h-
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O36030 (Residues: 1-391; Coverage: 100%)
Gene name: SPAC4F10.18
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

4 bound ligands:
Ligand SO4 1 x SO4
Ligand BU1 1 x BU1
Ligand DTT 1 x DTT
Ligand EDO 7 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41212
Unit cell:
a: 131.726Å b: 131.726Å c: 117.97Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.176 0.19
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

The Nuclear Pore Complex as a Flexible and Dynamic Gate.
Knockenhauer et al. (2016)
7 more

1 mention without citation

Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex.
Bilokapic et al. (2012)