› 4mh3

X-ray diffraction
2.4Å resolution

Crystal structure of Bovine Mitochondrial Peroxiredoxin III

Released:
DOI: 10.2210/pdb4mh3/pdb
PDB entry 4mh3 coloured by chain, front view.
PDB entry 4mh3 coloured by chain, side view.
PDB entry 4mh3 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Improved Catenated Structures of Bovine Peroxiredoxin III F190L Reveal Details of Ring-Ring Interactions and a Novel Conformational State.
Cao Z, McGow DP, Shepherd C, Lindsay JG
OpenAccess logo PLoS One 10 e0123303 (2015)
PMID: 25906064

Function and Biology Details

Reaction catalysed: 
Thioredoxin + ROOH = thioredoxin disulfide + H(2)O + ROH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin-dependent peroxide reductase, mitochondrial Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 220 amino acids
Theoretical weight: 24.35 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P35705 (Residues: 63-257; Coverage: 76%)
Gene names: AOP1, PRDX3
Sequence domains:
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:
Ligand CIT 3 x CIT
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P21212
Unit cell:
a: 142.895Å b: 290.885Å c: 81.139Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.221
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Taking Advantage of the Morpheein Behavior of Peroxiredoxin in Bionanotechnology.
Ardini et al. (2021)
4 other articles

1 mention without citation

Improved Catenated Structures of Bovine Peroxiredoxin III F190L Reveal Details of Ring-Ring Interactions and a Novel Conformational State.
Cao et al. (2015)