› 4msf

X-ray diffraction
1.98Å resolution

Crystal structure of the complex of goat lactoperoxidase with 3-hydroxymethyl phenol at 1.98 Angstrom resolution

Released:
DOI: 10.2210/pdb4msf/pdb
PDB entry 4msf coloured by chain, front view.
PDB entry 4msf coloured by chain, side view.
PDB entry 4msf coloured by chain, top view.
Source organism: Capra hircus
Entry authors: Singh A, Singh RP, Sinha M, Singh AK, Bhushan A, Kaur P, Sharma S, Singh TP

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105074 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactoperoxidase Chain: A
Molecule details ›
Chain: A
Length: 595 amino acids
Theoretical weight: 67.61 KDa
Source organism: Capra hircus
UniProt:
  • Canonical: A0A452E9Y6 (Residues: 118-712; Coverage: 86%)
Gene name: LPO
Sequence domains: Animal haem peroxidase
Structure domains: Haem peroxidase domain superfamily, animal type

Ligands and Environments


Cofactor: Ligand HEM 1 x HEM
7 bound ligands:
Ligand CA 1 x CA
Ligand NAG 4 x NAG
Ligand IOD 15 x IOD
Ligand SCN 1 x SCN
Ligand PEG 2 x PEG
Ligand EDO 2 x EDO
Ligand 3HY 1 x 3HY
1 modified residue:
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 53.766Å b: 80.356Å c: 75.76Å
α: 90° β: 102.71° γ: 90°
R-values:
R R work R free
0.194 0.192 0.238

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