4rnr

X-ray diffraction
2.76Å resolution

Crystal structure of broadly neutralizing anti-HIV antibody PGT130

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213614 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
PGT130 Heavy Chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 233 amino acids
Theoretical weight: 25.24 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
PGT130 Light Chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 216 amino acids
Theoretical weight: 22.86 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P212121
Unit cell:
a: 67.021Å b: 69.052Å c: 272.236Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.245 0.244 0.269
Expression system: Homo sapiens