4x2a

X-ray diffraction
2Å resolution

Crystal structure of mouse glyoxalase I complexed with baicalein

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-189993 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactoylglutathione lyase Chains: A, B
Molecule details ›
Chains: A, B
Length: 184 amino acids
Theoretical weight: 20.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9CPU0 (Residues: 1-184; Coverage: 100%)
Gene name: Glo1
Sequence domains: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Structure domains: 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCE ULTRA
Spacegroup: P21
Unit cell:
a: 41.501Å b: 64.502Å c: 63.152Å
α: 90° β: 104.79° γ: 90°
R-values:
R R work R free
0.174 0.171 0.218
Expression system: Escherichia coli