Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Protein-tyrosine kinase 2-beta and Leupaxin (preferred)
PDBe Complex ID:
PDB-CPX-130078 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein-tyrosine kinase 2-beta
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Focal adhesion targeting region
Structure domains: Nucleotidyltransferases domain 2
Length: 139 amino acids
Theoretical weight: 15.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q14289 (Residues: 871-1005; Coverage: 13%)
Sequence domains: Focal adhesion targeting region
Structure domains: Nucleotidyltransferases domain 2
Leupaxin
Molecule details ›
Chain: C
Length: 19 amino acids
Theoretical weight: 2.09 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 19 amino acids
Theoretical weight: 2.09 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: O60711 (Residues: 86-104; Coverage: 5%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 22-ID
Spacegroup:
P21212
Expression systems:
- Escherichia coli
- Not provided
