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4xrx Overview
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![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4xrx</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_deposited_chain_front_image-800x800.png "PDB entry 4xrx coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4xrx</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_deposited_chain_side_image-800x800.png "PDB entry 4xrx coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4xrx</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_deposited_chain_top_image-800x800.png "PDB entry 4xrx coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4xrx</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 4xrx coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4xrx</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 4xrx coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>4xrx</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 4xrx coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>4xrx</span> contains 2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_entity_1_front_image-800x800.png "Isocitrate dehydrogenase [NADP] cytoplasmic in PDB entry 4xrx, assembly 1, front view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>4xrx</span> contains 1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_entity_3_front_image-800x800.png "5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one in PDB entry 4xrx, assembly 1, front view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>4xrx</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Homo dimeric assembly 1 of PDB entry 4xrx coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>4xrx</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Homo dimeric assembly 1 of PDB entry 4xrx coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>4xrx</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP] cytoplasmic</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/4xrx_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Homo dimeric assembly 1 of PDB entry 4xrx coloured by chemically distinct molecules, top view.")