› 4zqy

X-ray diffraction
2.95Å resolution

Ringhalexin from hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex

Released:
DOI: 10.2210/pdb4zqy/pdb
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PDB entry 4zqy coloured by chain, front view.
PDB entry 4zqy coloured by chain, side view.
PDB entry 4zqy coloured by chain, top view.
Source organism: Hemachatus haemachatus
Primary publication:
Ringhalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex.
Barnwal B, Jobichen C, Girish VM, Foo CS, Sivaraman J, Kini RM
OpenAccess logo Sci Rep 6 25935 (2016)
PMID: 27173146

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-110950 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ringhalexin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 65 amino acids
Theoretical weight: 7.46 KDa
Source organism: Hemachatus haemachatus
UniProt:
  • Canonical: C0HJT5 (Residues: 1-65; Coverage: 100%)
Sequence domains: Snake toxin cobra-type
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P41212
Unit cell:
a: 82.16Å b: 82.16Å c: 82.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.217 0.268

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Citations

7 review citations

The chemistry of snake venom and its medicinal potential.
Oliveira et al. (2022)
6 more

4 mentions without citation

Ringhalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex.
Barnwal et al. (2016)
3 more

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