› 4a7w

X-ray diffraction
1.8Å resolution

Crystal structure of uridylate kinase from Helicobacter pylori

Released:
DOI: 10.2210/pdb4a7w/pdb
PDB entry 4a7w coloured by chain, front view.
PDB entry 4a7w coloured by chain, side view.
PDB entry 4a7w coloured by chain, top view.
Source organism: Helicobacter pylori 26695
Primary publication:
Structures of Helicobacter pylori uridylate kinase: insight into release of the product UDP.
Chu CH, Liu MH, Chen PC, Lin MH, Li YC, Hsiao CD, Sun YJ
Acta Crystallogr D Biol Crystallogr 68 773-83 (2012)
PMID: 22751662

Function and Biology Details

Reaction catalysed: 
ATP + UMP = ADP + UDP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157393 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uridylate kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 240 amino acids
Theoretical weight: 26.21 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P56106 (Residues: 1-240; Coverage: 100%)
Gene names: HP_0777, pyrH
Sequence domains: Amino acid kinase family
Structure domains: Acetylglutamate kinase-like

Ligands and Environments

2 bound ligands:
Ligand GTP 2 x GTP
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: R32
Unit cell:
a: 137.42Å b: 137.42Å c: 152.891Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.188 0.227
Expression system: Escherichia coli K-12

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Citations

1 citations in other articles

Phenotypic and Comparative Transcriptome Analysis of Different Ploidy Plants in Dendrocalamus latiflorus Munro.
Qiao et al. (2017)