4ag1

X-ray diffraction
1.4Å resolution

Function and Biology Details

Reaction catalysed:
Preferential cleavage: Phe-|- > Tyr-|- > Trp-|- > Leu-|-.
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-540640 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Chymase Chain: A
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 25.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
FYNOMER Chain: C
Molecule details ›
Chain: C
Length: 84 amino acids
Theoretical weight: 9.67 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 58.998Å b: 59.855Å c: 89.711Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.14 0.139 0.17
Expression system: Escherichia coli