Function and Biology

R121H - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis

Sequence family

Pfam Protein family (Pfam)
PF00074
Domain description: Pancreatic ribonuclease
Occurring in:
  1. Angiogenin
The deposited structure of PDB entry 4ahn contains 1 copy of Pfam domain PF00074 (Pancreatic ribonuclease) in Angiogenin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001427
Domain description: Pancreatic ribonuclease
Occurring in:
  1. Angiogenin
IPR023412
Domain description: Ribonuclease A-domain
Occurring in:
  1. Angiogenin
IPR036816
Domain description: Ribonuclease A-like domain superfamily
Occurring in:
  1. Angiogenin
IPR023411
Domain description: Ribonuclease A, active site
Occurring in:
  1. Angiogenin

Structure domain

CATH CATH domain
3.10.130.10
Class: Alpha Beta
Architecture: Roll
Topology: P-30 Protein
Homology: Ribonuclease A-like domain
Occurring in:
  1. Angiogenin
The deposited structure of PDB entry 4ahn contains 1 copy of CATH domain 3.10.130.10 (P-30 Protein) in Angiogenin. Showing 1 copy in chain A.