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Crystal structure of E. coli dihydrouridine synthase C (DusC)

Source organism: Escherichia coli K-12
Biochemical function: tRNA-dihydrouridine16 synthase activity
Biological process: gene expression
Cellular component: not assigned

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF01207
Domain description: Dihydrouridine synthase (Dus)
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
The deposited structure of PDB entry 4bfa contains 2 copies of Pfam domain PF01207 (Dihydrouridine synthase (Dus)) in tRNA-dihydrouridine(16) synthase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR035587
Domain description: DUS-like, FMN-binding domain
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
IPR042270
Domain description: tRNA-dihydrouridine(16) synthase, C-terminal
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
IPR018517
Domain description: tRNA-dihydrouridine synthase, conserved site
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
IPR032886
Domain description: tRNA-dihydrouridine(16) synthase
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
IPR013785
Domain description: Aldolase-type TIM barrel
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
IPR001269
Domain description: tRNA-dihydrouridine synthase
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
IPR038418
Domain description: 6-pyruvoyl tetrahydropterin synthase/QueD superfamily
Occurring in:
  1. tRNA-dihydrouridine(16) synthase

Structure domains

CATH CATH domains
1.20.225.30
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Bacteriocin As-48; Chain A
Homology: Dihydrouridine synthase, C-terminal recognition domain
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
The deposited structure of PDB entry 4bfa contains 2 copies of CATH domain 1.20.225.30 (Bacteriocin As-48; Chain A) in tRNA-dihydrouridine(16) synthase. Showing 1 copy in chain A.
3.20.20.70
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Aldolase class I
Occurring in:
  1. tRNA-dihydrouridine(16) synthase
The deposited structure of PDB entry 4bfa contains 2 copies of CATH domain 3.20.20.70 (TIM Barrel) in tRNA-dihydrouridine(16) synthase. Showing 1 copy in chain A.

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