› 4c5z

X-ray diffraction
2.5Å resolution

Crystal structure of A. niger ochratoxinase

Released:
DOI: 10.2210/pdb4c5z/pdb
PDB entry 4c5z coloured by chain, front view.
PDB entry 4c5z coloured by chain, side view.
PDB entry 4c5z coloured by chain, top view.
Source organism: Aspergillus niger
Primary publication:
Structural and functional characterization of ochratoxinase, a novel mycotoxin-degrading enzyme.
Dobritzsch D, Wang H, Schneider G, Yu S
Biochem J 462 441-52 (2014)
PMID: 24947135

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124420 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ochratoxinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 438 amino acids
Theoretical weight: 46.65 KDa
Source organism: Aspergillus niger
Expression system: Aspergillus niger
UniProt:
  • Canonical: G3XP38 (Residues: 43-480; Coverage: 91%)
Gene names: ASPNIDRAFT_41631, Am2
Sequence domains: Amidohydrolase family
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P4212
Unit cell:
a: 183.94Å b: 183.94Å c: 79.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.175 0.209
Expression system: Aspergillus niger

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Citations

8 review citations

Impact of food processing and detoxification treatments on mycotoxin contamination.
Karlovsky et al. (2016)
7 more