› 4d4t

X-ray diffraction
1.9Å resolution

RSV Matrix protein

Released:
DOI: 10.2210/pdb4d4t/pdb
PDB entry 4d4t coloured by chain, front view.
PDB entry 4d4t coloured by chain, side view.
PDB entry 4d4t coloured by chain, top view.
Source organism: Respiratory syncytial virus
Primary publication:
Dimerization of matrix protein is required for budding of respiratory syncytial virus.
Förster A, Maertens GN, Farrell PJ, Bajorek M
J Virol 89 4624-35 (2015)
PMID: 25673702

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143667 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Matrix protein Chain: A
Molecule details ›
Chain: A
Length: 258 amino acids
Theoretical weight: 29.02 KDa
Source organism: Respiratory syncytial virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DOE7 (Residues: 1-256; Coverage: 100%)
Gene name: M
Sequence domains: Pneumovirus matrix protein
Structure domains: HRSV-S2 matrix protein, N-terminal domain

Ligands and Environments

3 bound ligands:
Ligand GOL 1 x GOL
Ligand K 1 x K
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P6522
Unit cell:
a: 87.127Å b: 87.127Å c: 144.721Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.184 0.182 0.206
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

Respiratory syncytial virus entry and how to block it.
Battles et al. (2019)
8 more

2 mentions without citation

Dimerization of matrix protein is required for budding of respiratory syncytial virus.
Förster et al. (2015)
1 more