› › Function and Biology

Structure of POM1 FAB fragment complexed with human PrPc Fragment 120-230

Source organisms:
Biochemical function: not assigned
Biological process: protein homooligomerization
Cellular component: membrane

Quick links

GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00377
Domain description: Prion/Doppel alpha-helical domain
Occurring in:
  1. Major prion protein
The deposited structure of PDB entry 4dgi contains 1 copy of Pfam domain PF00377 (Prion/Doppel alpha-helical domain) in Major prion protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. POM1 Fab Heavy chain
  2. POM1 Fab Light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. POM1 Fab Heavy chain
  2. POM1 Fab Light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. POM1 Fab Heavy chain
  2. POM1 Fab Light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. POM1 Fab Heavy chain
  2. POM1 Fab Light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. POM1 Fab Heavy chain
  2. POM1 Fab Light chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. POM1 Fab Heavy chain
  2. POM1 Fab Light chain
IPR022416
Domain description: Prion/Doppel protein, beta-ribbon domain
Occurring in:
  1. Major prion protein
IPR036924
Domain description: Prion/Doppel beta-ribbon domain superfamily
Occurring in:
  1. Major prion protein
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. POM1 Fab Light chain
IPR003598
Domain description: Immunoglobulin subtype 2
Occurring in:
  1. POM1 Fab Light chain
IPR000817
Domain description: Prion protein
Occurring in:
  1. Major prion protein

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. POM1 Fab Heavy chain
  2. POM1 Fab Light chain
The deposited structure of PDB entry 4dgi contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in POM1 Fab Heavy chain. Showing 2 copies in chain B [auth H].
The deposited structure of PDB entry 4dgi contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in POM1 Fab Light chain. Showing 2 copies in chain C [auth L].
1.10.790.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Major Prion Protein
Homology: Prion/Doppel protein, beta-ribbon domain
Occurring in:
  1. Major prion protein
The deposited structure of PDB entry 4dgi contains 1 copy of CATH domain 1.10.790.10 (Major Prion Protein) in Major prion protein. Showing 1 copy in chain A.

Quick links