› 4f36

X-ray diffraction
2.3Å resolution

Crystal structure of Nucleoside diphosphate kinase B from Trypanosoma brucei, apo form

Released:
DOI: 10.2210/pdb4f36/pdb
PDB entry 4f36 coloured by chain, front view.
PDB entry 4f36 coloured by chain, side view.
PDB entry 4f36 coloured by chain, top view.
Source organism: Trypanosoma brucei brucei TREU927
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174323 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoside diphosphate kinase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 157 amino acids
Theoretical weight: 17.18 KDa
Source organism: Trypanosoma brucei brucei TREU927
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q381H3 (Residues: 1-153; Coverage: 100%)
Gene name: Tb11.01.7800
Sequence domains: Nucleoside diphosphate kinase
Structure domains: Nucleoside diphosphate kinase-like domain

Ligands and Environments

1 bound ligand:
Ligand SCN 1 x SCN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 52.46Å b: 123.67Å c: 145.36Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.235
Expression system: Escherichia coli BL21(DE3)

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