› 4f6o

X-ray diffraction
1.68Å resolution

Crystal structure of the yeast metacaspase Yca1

Released:
DOI: 10.2210/pdb4f6o/pdb
PDB entry 4f6o coloured by chain, front view.
PDB entry 4f6o coloured by chain, side view.
PDB entry 4f6o coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Crystal structure of the yeast metacaspase Yca1.
Wong AH, Yan C, Shi Y
J Biol Chem 287 29251-9 (2012)
PMID: 22761449

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170664 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metacaspase-1 Chain: A
Molecule details ›
Chain: A
Length: 350 amino acids
Theoretical weight: 38.61 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08601 (Residues: 83-432; Coverage: 81%)
Gene names: MCA1, YCA1, YOR197W
Sequence domains: Caspase domain

Ligands and Environments

1 bound ligand:
Ligand DFH 1 x DFH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: R3
Unit cell:
a: 114.627Å b: 114.627Å c: 62.101Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.171 0.17 0.187
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Evolution of caspase-mediated cell death and differentiation: twins separated at birth.
Bell et al. (2017)
9 more

7 mentions without citation

Crystal structure of the yeast metacaspase Yca1.
Wong et al. (2012)
6 more