4f7g

X-ray diffraction
2.05Å resolution

Crystal structure of talin autoinhibition complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150642 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Talin-1 Chain: A
Molecule details ›
Chain: A
Length: 222 amino acids
Theoretical weight: 25.61 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P26039 (Residues: 206-405; Coverage: 8%)
Gene names: Tln, Tln1
Sequence domains:
Structure domains:
Talin-1 Chain: B
Molecule details ›
Chain: B
Length: 216 amino acids
Theoretical weight: 22.86 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P26039 (Residues: 1654-1847; Coverage: 8%)
Gene names: Tln, Tln1
Sequence domains: Talin 1-like, rod segment domain
Structure domains: Talin, central domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 36.665Å b: 86.876Å c: 113.629Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.21 0.249
Expression system: Escherichia coli