Function and Biology Details
Reactions catalysed:
Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1' of the NS4A-NS4B cleavage site, whereas serine is found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
- not assigned
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Hog cholera virus (preferred)
PDBe Complex ID:
PDB-CPX-179319 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hog cholera virus
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.29 KDa
Source organism: Classical swine fever virus - Alfort/187
Expression system: Escherichia coli BL21
UniProt:
Structure domains: Pestivirus Npro endopeptidase C53, interaction domain
Length: 154 amino acids
Theoretical weight: 17.29 KDa
Source organism: Classical swine fever virus - Alfort/187
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q68871 (Residues: 18-168; Coverage: 4%)
Structure domains: Pestivirus Npro endopeptidase C53, interaction domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
BRUKER AXS MICROSTAR
Spacegroup:
P21212
Expression system: Escherichia coli BL21
