Function and Biology

Crystal structure of the full DNA binding domain of GATA3-complex 2

Source organism: Homo sapiens
Biochemical function: sequence-specific DNA binding
Biological process: regulation of transcription by RNA polymerase II
Cellular component: not assigned

Sequence family

Pfam Protein family (Pfam)
PF00320
Domain description: GATA zinc finger
Occurring in:
  1. Trans-acting T-cell-specific transcription factor GATA-3
The deposited structure of PDB entry 4hc7 contains 4 copies of Pfam domain PF00320 (GATA zinc finger) in Trans-acting T-cell-specific transcription factor GATA-3. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR000679
Domain description: Zinc finger, GATA-type
Occurring in:
  1. Trans-acting T-cell-specific transcription factor GATA-3
IPR013088
Domain description: Zinc finger, NHR/GATA-type
Occurring in:
  1. Trans-acting T-cell-specific transcription factor GATA-3
IPR039355
Domain description: Transcription factor GATA
Occurring in:
  1. Trans-acting T-cell-specific transcription factor GATA-3

Structure domain

CATH CATH domain
3.30.50.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Erythroid Transcription Factor GATA-1; Chain A
Homology: Erythroid Transcription Factor GATA-1, subunit A
Occurring in:
  1. Trans-acting T-cell-specific transcription factor GATA-3
The deposited structure of PDB entry 4hc7 contains 4 copies of CATH domain 3.30.50.10 (Erythroid Transcription Factor GATA-1; Chain A) in Trans-acting T-cell-specific transcription factor GATA-3. Showing 2 copies in chain A.