Function and Biology Details
Reaction catalysed:
Acetyl-CoA + an N-terminal-L-alanyl-[protein] = an N-terminal-N(alpha)-acetyl-L-alanyl-[protein] + CoA
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
N-terminal acetyltransferase A complex (preferred)
PDBe Complex ID:
PDB-CPX-139531 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
N-terminal acetyltransferase A complex subunit NAT1
Molecule details ›
Chains: A, C
Length: 863 amino acids
Theoretical weight: 100.13 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: N-terminal acetyltransferase A, auxiliary subunit
Length: 863 amino acids
Theoretical weight: 100.13 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical:
P12945 (Residues: 1-854; Coverage: 100%)
Sequence domains: N-terminal acetyltransferase A, auxiliary subunit
N-terminal acetyltransferase A complex catalytic subunit ARD1
Molecule details ›
Chains: B, D
Length: 248 amino acids
Theoretical weight: 28.82 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: Acetyltransferase (GNAT) family
Structure domains: Aminopeptidase
Length: 248 amino acids
Theoretical weight: 28.82 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: P07347 (Residues: 1-238; Coverage: 100%)
Sequence domains: Acetyltransferase (GNAT) family
Structure domains: Aminopeptidase
