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The crystal structure of isomaltulose synthase from Erwinia rhapontici NX5 in complex with Tris

Source organism: Erwinia rhapontici
Biochemical function: metal ion binding
Biological process: oligosaccharide catabolic process
Cellular component: not assigned

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EC 5.4.99.11: Isomaltulose synthase

Reaction catalysed:
Sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose
Systematic name:
Sucrose glucosylmutase
Alternative Name(s):
  • Isomaltulose synthetase
  • Sucrose alpha-glucosyltransferase
  • Trehalulose synthase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF16657
Domain description: Maltogenic Amylase, C-terminal domain
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
The deposited structure of PDB entry 4hox contains 1 copy of Pfam domain PF16657 (Maltogenic Amylase, C-terminal domain) in Glycosyl hydrolase family 13 catalytic domain-containing protein. Showing 1 copy in chain A.

PF00128
Domain description: Alpha amylase, catalytic domain
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
The deposited structure of PDB entry 4hox contains 1 copy of Pfam domain PF00128 (Alpha amylase, catalytic domain) in Glycosyl hydrolase family 13 catalytic domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006047
Domain description: Glycosyl hydrolase, family 13, catalytic domain
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
IPR013780
Domain description: Glycosyl hydrolase, all-beta
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
IPR032091
Domain description: Maltogenic amylase-like, C-terminal
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
IPR045857
Domain description: Oligo-1,6-glucosidase, domain 2
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein

Structure domains

CATH CATH domains
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
The deposited structure of PDB entry 4hox contains 1 copy of CATH domain 3.20.20.80 (TIM Barrel) in Glycosyl hydrolase family 13 catalytic domain-containing protein. Showing 1 copy in chain A.
2.60.40.1180
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Golgi alpha-mannosidase II
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
The deposited structure of PDB entry 4hox contains 1 copy of CATH domain 2.60.40.1180 (Immunoglobulin-like) in Glycosyl hydrolase family 13 catalytic domain-containing protein. Showing 1 copy in chain A.
3.90.400.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Oligo-1,6-glucosidase; domain 2
Homology: Oligo-1,6-glucosidase; Domain 2
Occurring in:
  1. Glycosyl hydrolase family 13 catalytic domain-containing protein
The deposited structure of PDB entry 4hox contains 1 copy of CATH domain 3.90.400.10 (Oligo-1,6-glucosidase; domain 2) in Glycosyl hydrolase family 13 catalytic domain-containing protein. Showing 1 copy in chain A.

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