Function and Biology Details
Reaction catalysed:
ATP + [biotin carboxyl-carrier protein]-biotin-N(6)-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N(6)-L-lysine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142043 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Biotin carboxylase
Molecule details ›
Chains: A, C, E, F
Length: 449 amino acids
Theoretical weight: 49.39 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 449 amino acids
Theoretical weight: 49.39 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P24182 (Residues: 1-449; Coverage: 100%)
Sequence domains:
- Biotin carboxylase, N-terminal domain
- Carbamoyl-phosphate synthase L chain, ATP binding domain
- Biotin carboxylase C-terminal domain
Biotin carboxyl carrier protein of acetyl-CoA carboxylase
Molecule details ›
Chains: B, D, G, I
Length: 176 amino acids
Theoretical weight: 18.87 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Biotin-requiring enzyme
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Length: 176 amino acids
Theoretical weight: 18.87 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P0ABD8 (Residues: 1-156; Coverage: 100%)
Sequence domains: Biotin-requiring enzyme
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
