4jha

X-ray diffraction
1.6Å resolution

Crystal Structure of RSV-Neutralizing Human Antibody D25

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213508 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
D25 antigen-binding fragment heavy chain Chain: H
Molecule details ›
Chain: H
Length: 231 amino acids
Theoretical weight: 24.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
D25 light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.33 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P6122
Unit cell:
a: 108.725Å b: 108.725Å c: 139.909Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.241 0.24 0.255
Expression system: Homo sapiens