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The crystal structure of the RPGR RCC1-like domain in complex with PDE6D

Source organism: Homo sapiens
Biochemical function: small GTPase binding
Biological process: sensory perception of light stimulus
Cellular component: cell projection

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00415
Domain description: Regulator of chromosome condensation (RCC1) repeat
Occurring in:
  1. X-linked retinitis pigmentosa GTPase regulator
The deposited structure of PDB entry 4jhp contains 6 copies of Pfam domain PF00415 (Regulator of chromosome condensation (RCC1) repeat) in X-linked retinitis pigmentosa GTPase regulator. Showing 6 copies in chain B [auth C].

PF05351
Domain description: GMP-PDE, delta subunit
Occurring in:
  1. Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
The deposited structure of PDB entry 4jhp contains 1 copy of Pfam domain PF05351 (GMP-PDE, delta subunit) in Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta. Showing 1 copy in chain A [auth B].

InterPro InterPro annotations
IPR000408
Domain description: Regulator of chromosome condensation, RCC1
Occurring in:
  1. X-linked retinitis pigmentosa GTPase regulator
IPR009091
Domain description: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Occurring in:
  1. X-linked retinitis pigmentosa GTPase regulator
IPR008015
Domain description: GMP phosphodiesterase, delta subunit
Occurring in:
  1. Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
IPR014756
Domain description: Immunoglobulin E-set
Occurring in:
  1. Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
IPR017287
Domain description: Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit
Occurring in:
  1. Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
IPR037036
Domain description: GMP phosphodiesterase, delta subunit superfamily
Occurring in:
  1. Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

Structure domains

CATH CATH domains
2.130.10.30
Class: Mainly Beta
Architecture: 7 Propeller
Topology: Methylamine Dehydrogenase; Chain H
Homology: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Occurring in:
  1. X-linked retinitis pigmentosa GTPase regulator
The deposited structure of PDB entry 4jhp contains 1 copy of CATH domain 2.130.10.30 (Methylamine Dehydrogenase; Chain H) in X-linked retinitis pigmentosa GTPase regulator. Showing 1 copy in chain B [auth C].
2.70.50.40
Class: Mainly Beta
Architecture: Distorted Sandwich
Topology: Coagulation Factor XIII; Chain A, domain 1
Homology: GMP phosphodiesterase, delta subunit
Occurring in:
  1. Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
The deposited structure of PDB entry 4jhp contains 1 copy of CATH domain 2.70.50.40 (Coagulation Factor XIII; Chain A, domain 1) in Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta. Showing 1 copy in chain A [auth B].

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