› 4jzq

X-ray diffraction
1.35Å resolution

Crystal structure of human CLIC1 C24D mutant

Released:
DOI: 10.2210/pdb4jzq/pdb
PDB entry 4jzq coloured by chain, front view.
PDB entry 4jzq coloured by chain, side view.
PDB entry 4jzq coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Phang JM, Harrop SJ, Duff AP, Wilk KE, Curmi PMG

Function and Biology Details

Reaction catalysed: 
2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-517204 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chloride intracellular channel protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 243 amino acids
Theoretical weight: 27.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00299 (Residues: 1-241; Coverage: 100%)
Gene names: CLIC1, G6, NCC27
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P21
Unit cell:
a: 42.381Å b: 69.691Å c: 83.42Å
α: 90° β: 90.1° γ: 90°
R-values:
R R work R free
0.153 0.151 0.182
Expression system: Escherichia coli BL21(DE3)

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