Function and Biology Details
Reactions catalysed:
L-alanine + glyoxylate = pyruvate + glycine
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Tetratricopeptide repeat
- Tetratricopeptide-like helical domain superfamily
- PEX5/PEX5L
- Aminotransferase class-V, pyridoxal-phosphate binding site
- Aminotransferase class V domain
- Pyridoxal phosphate-dependent transferase, major domain
- Pyridoxal phosphate-dependent transferase, small domain
- Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase
1 more domain
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149290 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alanine--glyoxylate aminotransferase
Molecule details ›
Chains: A, C
Length: 394 amino acids
Theoretical weight: 43.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Aminotransferase class-V
Structure domains:
Length: 394 amino acids
Theoretical weight: 43.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P21549 (Residues: 1-392; Coverage: 100%)
Sequence domains: Aminotransferase class-V
Structure domains:
Peroxisomal targeting signal 1 receptor
Molecule details ›
Chains: B, D
Length: 328 amino acids
Theoretical weight: 36.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Tetratricopeptide repeat domain
Length: 328 amino acids
Theoretical weight: 36.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P50542 (Residues: 315-639; Coverage: 51%)
Sequence domains:
Structure domains: Tetratricopeptide repeat domain
