Function and Biology

Rat PKC C2 domain bound to CD

Source organism: Rattus norvegicus
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 2.7.11.13: Protein kinase C

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Systematic name:
ATP:protein phosphotransferase (diacylglycerol-dependent)
Alternative Name(s):
  • CPKC
  • CPKC-alpha
  • CPKC-beta
  • CPKC-gamma
  • Calcium-dependent protein kinase C
  • Calcium-independent protein kinase C
  • Calcium/phospholipid dependent protein kinase
  • NPKC
  • NPKC-delta
  • NPKC-epsilon
  • NPKC-eta
  • NPKC-theta
  • PKC
  • PKC-alpha
  • PKC-beta
  • PKC-delta
  • PKC-epsilon
  • PKC-gamma
  • PKC-zeta
  • Pkc1p
  • Protein kinase C-epsilon
  • STK24

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00168
Domain description: C2 domain
Occurring in:
  1. Protein kinase C alpha type
The deposited structure of PDB entry 4l1l contains 1 copy of Pfam domain PF00168 (C2 domain) in Protein kinase C alpha type. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000008
Domain description: C2 domain
Occurring in:
  1. Protein kinase C alpha type
IPR035892
Domain description: C2 domain superfamily
Occurring in:
  1. Protein kinase C alpha type
IPR043566
Domain description: Rabphilin/Doc2/Noc2
Occurring in:
  1. Protein kinase C alpha type

Structure domain

CATH CATH domain
2.60.40.150
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: C2 domain
Occurring in:
  1. Protein kinase C alpha type
The deposited structure of PDB entry 4l1l contains 1 copy of CATH domain 2.60.40.150 (Immunoglobulin-like) in Protein kinase C alpha type. Showing 1 copy in chain A.