4la6

X-ray diffraction
2Å resolution

Crystal structure of 2-methylisoborneol synthase from Streptomyces coelicolor A3(2) in complex with Mg2+ and 2-fluoroneryl diphosphate

Released:

Function and Biology Details

Reaction catalysed:
(E)-2-methylgeranyl diphosphate + H(2)O = 2-methylisoborneol + diphosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-190241 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-methylisoborneol synthase Chain: A
Molecule details ›
Chain: A
Length: 461 amino acids
Theoretical weight: 50.14 KDa
Source organism: Streptomyces coelicolor A3(2)
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9F1Y6 (Residues: 1-440; Coverage: 100%)
Gene names: SC1A4.08, SCBAC12C8.01, SCO7700
Sequence domains: Terpene synthase family 2, C-terminal metal binding
Structure domains: Farnesyl Diphosphate Synthase

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P4322
Unit cell:
a: 99.462Å b: 99.462Å c: 105.079Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.173 0.201
Expression system: Escherichia coli BL21(DE3)