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ARNT transcription factor/coactivator complex

X-ray diffraction
3.15Å resolution
PDB entry 4lpz coloured by chain, front view.
PDB entry 4lpz coloured by chain, side view.
PDB entry 4lpz coloured by chain, top view.
Source organisms:
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Transforming acidic coiled-coil-containing protein 3 and Aryl hydrocarbon receptor nuclear translocator
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Multimeric state: hetero tetramer
Accessible surface area: 13380.11 Å2
Buried surface area: 3982.0 Å2
Dissociation area: 581.76 Å2
Dissociation energy (ΔGdiss): -0.29 kcal/mol
Dissociation entropy (TΔSdiss): 11.47 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-151029

Macromolecules

Aryl hydrocarbon receptor nuclear translocator
Chains: A, B
Length: 119 amino acids
Theoretical weight: 13.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P27540 (Residues: 356-470; Coverage: 15%)
Gene names: ARNT, BHLHE2
Pfam: PAS domain
InterPro:
CATH: PAS domain
Aryl hydrocarbon receptor nuclear translocator in PDB entry 4lpz, assembly 1, front view.
Aryl hydrocarbon receptor nuclear translocator in PDB entry 4lpz, assembly 1, side view.
Aryl hydrocarbon receptor nuclear translocator in PDB entry 4lpz, assembly 1, top view.
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Transforming acidic coiled-coil-containing protein 3
Chains: C, D
Length: 44 amino acids
Theoretical weight: 5.08 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JJ11 (Residues: 603-631; Coverage: 5%)
Gene names: Aint, Tacc3
InterPro: Basic-leucine zipper domain superfamily
Transforming acidic coiled-coil-containing protein 3 in PDB entry 4lpz, assembly 1, front view.
Transforming acidic coiled-coil-containing protein 3 in PDB entry 4lpz, assembly 1, side view.
Transforming acidic coiled-coil-containing protein 3 in PDB entry 4lpz, assembly 1, top view.
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