EC 2.7.6.1: Ribose-phosphate diphosphokinase
Reaction catalysed:
ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate
Systematic name:
ATP:D-ribose-5-phosphate diphosphotransferase
Alternative Name(s):
- 5-phosphoribose pyrophosphorylase
- 5-phosphoribosyl-1-pyrophosphate synthetase
- 5-phosphoribosyl-alpha-1-pyrophosphate synthetase
- PP-ribose P synthetase
- PPRibP synthetase
- PRPP synthetase
- Phosphoribosyl diphosphate synthetase
- Phosphoribosyl pyrophosphate synthetase
- Phosphoribosyl-diphosphate synthetase
- Phosphoribosylpyrophosphate synthase
- Phosphoribosylpyrophosphate synthetase
- Pyrophosphoribosylphosphate synthetase
- Ribophosphate pyrophosphokinase
- Ribose-5-phosphate pyrophosphokinase
- Ribose-phosphate pyrophosphokinase
GO terms
Biochemical function:
Biological process:
- organophosphate biosynthetic process
- hypoxanthine biosynthetic process
- cellular biosynthetic process
- urate biosynthetic process
- nucleotide biosynthetic process
- ribonucleoside monophosphate biosynthetic process
- nervous system development
- phosphate-containing compound metabolic process
- pyrimidine nucleotide biosynthetic process
- purine nucleotide biosynthetic process
- purine nucleobase metabolic process
- 5-phosphoribose 1-diphosphate biosynthetic process
Protein families (Pfam)
InterPro annotations
CATH domain