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Methanol dehydrogenase from Methylacidiphilum fumariolicum SolV

Source organism: Methylacidiphilum fumariolicum SolV
Biochemical function: alcohol dehydrogenase (cytochrome c) activity
Biological process: methanol metabolic process
Cellular component: periplasmic space

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EC 1.1.2.8: Alcohol dehydrogenase (cytochrome c)

Reaction catalysed:
A primary alcohol + 2 cytochrome c = an aldehyde + 2 reduced cytochrome c + 2 H(+)
Systematic name:
Alcohol:cytochrome c oxidoreductase
Alternative Name(s):
  • Quinoprotein ethanol dehydrogenase
  • Type I quinoprotein alcohol dehydrogenase

EC 1.1.2.7: Methanol dehydrogenase (cytochrome c)

Reaction catalysed:
A primary alcohol + 2 cytochrome c(L) = an aldehyde + 2 reduced cytochrome c(L) + 2 H(+)
Systematic name:
Methanol:cytochrome c oxidoreductase
Alternative Name(s):
  • MDH
  • Methanol dehydrogenase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF13570
Domain description: PQQ-like domain
Occurring in:
  1. Lanthanide-dependent methanol dehydrogenase
The deposited structure of PDB entry 4mae contains 2 copies of Pfam domain PF13570 (PQQ-like domain) in Methanol dehydrogenase. Showing 1 copy in chain A.

PF13360
Domain description: PQQ-like domain
Occurring in:
  1. Lanthanide-dependent methanol dehydrogenase
The deposited structure of PDB entry 4mae contains 2 copies of Pfam domain PF13360 (PQQ-like domain) in Methanol dehydrogenase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR018391
Domain description: Pyrrolo-quinoline quinone beta-propeller repeat
Occurring in:
  1. Lanthanide-dependent methanol dehydrogenase
IPR002372
Domain description: Pyrrolo-quinoline quinone repeat
Occurring in:
  1. Lanthanide-dependent methanol dehydrogenase
IPR011047
Domain description: Quinoprotein alcohol dehydrogenase-like superfamily
Occurring in:
  1. Lanthanide-dependent methanol dehydrogenase
IPR017512
Domain description: PQQ-dependent dehydrogenase, methanol/ethanol family
Occurring in:
  1. Lanthanide-dependent methanol dehydrogenase

Structure domain

CATH CATH domain
2.140.10.10
Class: Mainly Beta
Architecture: 8 Propeller
Topology: Methanol Dehydrogenase; Chain A
Homology: Quinoprotein alcohol dehydrogenase-like superfamily
Occurring in:
  1. Lanthanide-dependent methanol dehydrogenase
The deposited structure of PDB entry 4mae contains 2 copies of CATH domain 2.140.10.10 (Methanol Dehydrogenase; Chain A) in Methanol dehydrogenase. Showing 1 copy in chain A.

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